Tearsheet

Salarius Pharmaceuticals (SLRX)


Market Price (1/8/2026): $0.8733 | Market Cap: $0.4 Mil
Sector: Health Care | Industry: Biotechnology

Salarius Pharmaceuticals (SLRX)


Market Price (1/8/2026): $0.8733
Market Cap: $0.4 Mil
Sector: Health Care
Industry: Biotechnology

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.


0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -1189%
Weak multi-year price returns
2Y Excs Rtn is -146%, 3Y Excs Rtn is -180%
Penny stock
Mkt Price is 0.8
1 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, Biopharmaceutical R&D, Show more.
  Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
2   Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -5.1 Mil
3   Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -1241%
4   High stock price volatility
Vol 12M is 203%
5   Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 38%
6   Key risks
SLRX key risks include [1] substantial doubt about its ability to continue as a going concern due to severe financial distress, Show more.
0 Cash is significant % of market cap
Net D/ENet Debt/Equity. Debt net of cash. Negative indicates net cash. Equity is taken as the Market Capitalization is -1189%
1 Megatrend and thematic drivers
Megatrends include Aging Population & Chronic Disease, and Precision Medicine. Themes include Oncology Treatments, Biopharmaceutical R&D, Show more.
2 Weak multi-year price returns
2Y Excs Rtn is -146%, 3Y Excs Rtn is -180%
3 Penny stock
Mkt Price is 0.8
4 Very low revenue
Rev LTMTotal Revenue or Sales, Last Twelve Months is 0
5 Not profitable at operating income level
Op Inc LTMOperating Income, Last Twelve Months is -5.1 Mil
6 Yield minus risk free rate is negative
ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is -1241%
7 High stock price volatility
Vol 12M is 203%
8 Significant short interest
Short Interest % of Basic SharesShort Interest % of Basic Shares = (Short Interest Quantity) / (Basic Shares Outstanding). A high fraction of short interest can indicate potential risk of a short squeeze. is 38%
9 Key risks
SLRX key risks include [1] substantial doubt about its ability to continue as a going concern due to severe financial distress, Show more.

Valuation, Metrics & Events

SLRX Stock


Why The Stock Moved


Qualitative Assessment

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1. Salarius Pharmaceuticals received a Nasdaq delisting notice due to its common stock falling below the $1.00 minimum bid price for 30 consecutive business days by December 31, 2025. This notice indicated that the company's securities were scheduled for suspension and delisting by January 9, 2026, unless an appeal was successful.

2. The company was not eligible for the standard 180-day compliance period to regain Nasdaq listing requirements. This ineligibility stemmed from a previous reverse stock split within the prior year and the company being under a Mandatory Panel Monitor.

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Stock Movement Drivers

Fundamental Drivers

The -78.4% change in SLRX stock from 10/31/2025 to 1/7/2026 was primarily driven by a -240.3% change in the company's Shares Outstanding (Mil).
103120251072026Change
Stock Price ($)3.890.84-78.41%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)0.000.00�
P/S Multiple∞∞�
Shares Outstanding (Mil)0.140.48-240.29%
Cumulative Contribution�

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 1/7/2026
ReturnCorrelation
SLRX-78.4% 
Market (SPY)1.1%10.4%
Sector (XLV)10.7%6.6%

Fundamental Drivers

The -90.7% change in SLRX stock from 7/31/2025 to 1/7/2026 was primarily driven by a -334.1% change in the company's Shares Outstanding (Mil).
73120251072026Change
Stock Price ($)8.990.84-90.66%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)0.000.00�
P/S Multiple∞∞�
Shares Outstanding (Mil)0.110.48-334.14%
Cumulative Contribution�

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 1/7/2026
ReturnCorrelation
SLRX-90.7% 
Market (SPY)9.4%8.2%
Sector (XLV)23.0%5.1%

Fundamental Drivers

The -97.5% change in SLRX stock from 1/31/2025 to 1/7/2026 was primarily driven by a -463.5% change in the company's Shares Outstanding (Mil).
13120251072026Change
Stock Price ($)33.600.84-97.50%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)0.000.00�
P/S Multiple∞∞�
Shares Outstanding (Mil)0.090.48-463.54%
Cumulative Contribution�

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2025 to 1/7/2026
ReturnCorrelation
SLRX-97.5% 
Market (SPY)15.6%-5.3%
Sector (XLV)10.2%-8.4%

Fundamental Drivers

The -99.7% change in SLRX stock from 1/31/2023 to 1/7/2026 was primarily driven by a -9.2233720368547763E17% change in the company's P/S Multiple.
13120231072026Change
Stock Price ($)309.600.84-99.73%
Change Contribution ByLTMLTM
Total Revenues ($ Mil)-1.840.00-100.00%
P/S Multiple-3.15∞-∞%
Shares Outstanding (Mil)0.020.48-2471.07%
Cumulative Contribution�

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2023 to 1/7/2026
ReturnCorrelation
SLRX-99.7% 
Market (SPY)76.0%-0.7%
Sector (XLV)25.3%-3.3%

Return vs. Risk


Price Returns Compared

 202120222023202420252026Total [1]
Returns
SLRX Return-46%-88%-58%-65%-98%0%-100%
Peers Return-4%-65%-3%15%27%-1%-53%
S&P 500 Return27%-19%24%23%16%1%85%

Monthly Win Rates [3]
SLRX Win Rate25%17%25%33%33%100% 
Peers Win Rate58%35%37%45%53%40% 
S&P 500 Win Rate75%42%67%75%67%100% 

Max Drawdowns [4]
SLRX Max Drawdown-46%-91%-63%-77%-98%-18% 
Peers Max Drawdown-29%-73%-65%-34%-58%-6% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%0% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: ARVN, KYMR, NRIX, CCCC, GLUE. See SLRX Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 1/7/2026 (YTD)

How Low Can It Go

Unique KeyEventSLRXS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-99.3%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven13257.1%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-85.2%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven575.6%51.3%
2020 Covid PandemicTime to BreakevenTime to BreakevenNot Fully Recovered days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-98.4%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven6191.4%24.7%
2018 CorrectionTime to BreakevenTime to BreakevenNot Fully Recovered days120 days

Compare to ARVN, KYMR, NRIX, CCCC, GLUE

In The Past

Salarius Pharmaceuticals's stock fell -99.3% during the 2022 Inflation Shock from a high on 2/10/2021. A -99.3% loss requires a 13257.1% gain to breakeven.

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About Salarius Pharmaceuticals (SLRX)

Salarius Pharmaceuticals, Inc., a clinical-stage biotechnology company, focuses on developing epigenetic-based cancer treatments. Its lead candidate is Seclidemstat (SP-2577), a small molecular inhibitor which is in Phase I/II clinical trial for the treatment of advanced solid tumors, as well as Ewing sarcoma. The company also offers SP-3164, a small molecular protein degrader for the treatment of hematological and solid tumors. It has a strategic partnership with The University of Utah Research Foundation for the exclusive license with respect to patent rights protecting SP-2577 and related compounds; HLB Life Sciences to develop, produce, manufacture, use, and sell the drug in South Korea; and Cancer Prevention and Research Institute of Texas for product development activities, as well as a research partnership with the Cancer Epigenetics Institute at Fox Chase Cancer Center to identify new indications and biomarkers for SP-2577. The company is headquartered in Houston, Texas.

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Here are 1-3 brief analogies for Salarius Pharmaceuticals (SLRX):

  • An early-stage Blueprint Medicines, but focused on epigenetic cancer drugs.
  • A small, clinical-stage Genentech, but dedicated to novel epigenetic cancer treatments.
  • An early-stage Agios Pharmaceuticals, but exclusively concentrated on epigenetic cancer therapies.

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  • Seclinsastat (SP-2577): An investigational, orally bioavailable LSD1 inhibitor being developed for the treatment of various cancers, including Ewing sarcoma and myelofibrosis.

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Salarius Pharmaceuticals (SLRX) is a clinical-stage oncology company focused on the development of epigenetic therapies for cancer. As of current information, the company does not have any commercialized pharmaceutical products on the market.

Therefore, Salarius Pharmaceuticals does not currently have major commercial customers in the traditional sense of companies or individuals purchasing its products. Its activities are primarily focused on research and development, conducting clinical trials for its drug candidates, and securing funding for these operations.

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Mark J. Rosenblum Acting Chief Executive Officer, Executive Vice President, Chief Financial Officer

Mr. Rosenblum was appointed acting Chief Executive Officer of Salarius Pharmaceuticals on August 17, 2025, while continuing his roles as Executive Vice President and Chief Financial Officer, positions he has held since September 2019. He initially joined Salarius as a financial consultant to assist with the merger of Flex Pharma, Inc. and Salarius Pharmaceuticals, LLC. Prior to Salarius, Mr. Rosenblum served as Chairman and Chief Executive Officer of ActiveCare, Inc. (formerly NASDAQ: ACAR), which was acquired by Biotelemetry, Inc., now part of Royal Philips. He also held the position of Chief Financial Officer at Advaxis, Inc. (NASDAQ: ADXS) and various financial leadership roles at Wellman, Inc., a public chemical manufacturer.

Nadeem Q. Mirza, MD, MPH Senior Vice President, Clinical Development

Dr. Mirza serves as the Senior Vice President of Clinical Development at Salarius Pharmaceuticals.

Rebecca Griffith-Eskew Vice President, Clinical Operations

Mrs. Griffith-Eskew is the Vice President of Clinical Operations for Salarius Pharmaceuticals. She brings over 25 years of experience in clinical development and operations, specifically in oncology drug development across phases I-IV.

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Key Risks to Salarius Pharmaceuticals (SLRX)

Salarius Pharmaceuticals (SLRX) faces several significant risks that could impact its business operations and future viability. The most pressing concerns revolve around its precarious financial position, the uncertainties surrounding its proposed merger, and the inherent challenges of clinical-stage drug development.

  1. Financial Distress and Going Concern Uncertainty: Salarius Pharmaceuticals is in a highly challenging financial situation, marked by recurring losses and a lack of revenue from product sales. The company has explicitly stated that there is "substantial doubt about its ability to continue as a going concern". As of March 31, 2025, Salarius had limited cash and cash equivalents, necessitating continuous reliance on external funding to sustain operations. The company's probability of financial distress or bankruptcy is estimated to be very high.
  2. Risks Associated with the Proposed Merger with Decoy Therapeutics: Salarius has entered into a merger agreement with Decoy Therapeutics, which, while intended to be a strategic alternative to address financial challenges, introduces a new set of substantial risks. Key concerns include the potential failure to satisfy closing conditions, uncertainties regarding the timing and consummation of the merger, and the risk that the combined entity may not achieve expected synergies. Furthermore, if the merger is completed, Salarius stockholders face significant dilution, with Decoy investors expected to own approximately 86% of the outstanding shares of the merged company. There is also a risk that the combined company will not secure sufficient financing to execute its business plans or maintain Nasdaq listing standards. Should the merger not close, Salarius may be forced to seek alternative capital or consider winding down operations.
  3. Clinical Development and Regulatory Risks: As a clinical-stage biopharmaceutical company, Salarius' future is heavily dependent on the successful development and regulatory approval of its drug candidates. The company has already discontinued a Phase 1/2 clinical trial for SP-2577 in Ewing sarcoma due to financial constraints. The combined company (post-merger with Decoy Therapeutics) will face ongoing risks related to Decoy's product development plans and potential unanticipated issues with investigational new drug applications. Additionally, Salarius has previously experienced setbacks, including a partial clinical hold by the U.S. Food and Drug Administration following a Grade 4 adverse event in a clinical trial.

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Salarius Pharmaceuticals (SLRX) focuses on developing treatments for cancers with high unmet medical needs. The addressable markets for their main products and services, including those from the recently merged Decoy Therapeutics, are detailed below.

Seclidemstat (SP-2577)

  • Ewing Sarcoma: The global market for Ewing sarcoma across the seven major markets (United States, EU4, United Kingdom, and Japan) was valued at approximately USD 49.8 million in 2024 and is projected to reach USD 78.2 million by 2035, growing at a Compound Annual Growth Rate (CAGR) of 4.2%. Another estimate places the global market at USD 250.94 million in 2025, anticipating it to exceed USD 436.84 million by 2035 with a CAGR of over 5.7%. The United States has the largest patient pool and represents the largest market for Ewing sarcoma treatment. Annually, around 500 new patients are diagnosed with Ewing sarcoma in the U.S..
  • Myelodysplastic Syndromes (MDS): The market for myelodysplastic syndrome drugs across the top seven major markets (United States, EU4, United Kingdom, and Japan) was valued at USD 2.4 billion in 2024 and is projected to reach USD 4.8 billion by 2035, exhibiting a CAGR of 6.29%. The global MDS drug market was estimated at USD 2.2 billion in 2023 and is projected to reach USD 4.1 billion by 2030, with a CAGR of 9.1%. In 2024, the global myelodysplastic syndrome market size was valued at $2.56 billion and is expected to grow to $4.18 billion by 2029 at a CAGR of 10.1%. The United States accounts for the largest patient pool and market for MDS treatment.
  • Chronic Myelomonocytic Leukemia (CMML): The global chronic myelomonocytic leukemia market is estimated to be valued at USD 1012.9 million in 2025 and is expected to reach USD 1584.4 million by 2032, with a CAGR of 6.6%. Another report indicates that the global CMML market was approximately USD 720 million in 2024 and is projected to reach USD 1.45 billion by 2034, with a CAGR of 7.1%. Approximately 1,500 new CMML cases are diagnosed annually in the United States. North America is currently the largest market for CMML.

SP-3164 (Targeted Protein Degrader)

SP-3164 has potential applications in both hematologic and solid tumors.

  • Hematologic Malignancies: The global hematologic malignancies market size was estimated at USD 67,234.0 million in 2023 and is projected to reach USD 113,897.9 million by 2030, growing at a CAGR of 8.0%. North America represented the largest revenue-generating market in 2023, with the U.S. holding an 89.3% share within North America. In 2024, the global hematologic malignancies market was valued at USD 72.87 billion and is expected to reach USD 147.38 billion by 2033, exhibiting a CAGR of 8.14%.
  • Solid Tumors: The global solid tumors market size was valued at USD 362.21 billion in 2024 and is projected to reach USD 1557.42 billion by 2032, with a CAGR of 20.00%. The solid tumors market across the top seven major markets (United States, EU4, United Kingdom, and Japan) reached USD 183.0 billion in 2024 and is expected to reach USD 406.4 billion by 2035, with a CAGR of 7.53%. North America dominates the solid tumors market. The U.S. solid tumor cancer treatment market size was valued at USD 1.32 billion in 2024 and is predicted to reach approximately USD 2.19 billion by 2034.

Decoy Therapeutics (Post-Merger Pipeline)

The combined company, Decoy Therapeutics, will focus on peptide conjugate therapeutics for respiratory viruses and cancer, with Decoy's pipeline targeting unmet needs in respiratory infectious diseases and gastroenterology (GI) oncology indications.

  • Infectious Respiratory Diseases: The global infectious respiratory disease diagnostics market size was estimated at USD 54.58 billion in 2024 and is projected to reach USD 73.56 billion by 2030, with a CAGR of 5.3%. North America dominated the global market, accounting for 41.85% of revenue share in 2024. The U.S. infectious respiratory disease diagnostics market size was evaluated at USD 17.21 billion in 2024 and is predicted to be worth around USD 29.49 billion by 2034.
  • Gastrointestinal (GI) Oncology: The global gastrointestinal cancer treatment market size was valued at approximately USD 12.5 billion in 2023 and is forecasted to reach nearly USD 21.4 billion by 2032, with a CAGR of 7.2%. The global gastrointestinal cancer market accounted for USD 27.46 billion in 2024 and is expected to reach USD 93.48 billion by 2035, growing at a CAGR of approximately 11.78%. North America holds a significant share of the global gastrointestinal cancer treatment market, with a value of approximately USD 4.5 billion in 2023 and a projection to reach nearly USD 7.5 billion by 2032.

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Expected Drivers of Future Revenue Growth for Salarius Pharmaceuticals (SLRX)

Over the next 2-3 years, the future revenue growth for Salarius Pharmaceuticals (SLRX), which is merging with Decoy Therapeutics to become Decoy Therapeutics, is expected to be driven by several key factors primarily related to the advancement and potential commercialization of their therapeutic pipeline.

  1. Advancement and Potential Approval of Seclidemstat (SP-2577) for Ewing Sarcoma: Salarius' lead candidate, seclidemstat (SP-2577), is a first-in-class LSD1 inhibitor currently in a Phase 1/2 clinical trial for relapsed/refractory Ewing sarcoma. This indication has a high unmet medical need and has received Fast Track Designation, Orphan Drug Designation, and Rare Pediatric Disease Designation from the U.S. Food and Drug Administration (FDA), which could expedite its path to market. Successful clinical outcomes and subsequent regulatory approval would be a significant revenue driver.
  2. Clinical Progress and Potential Approval of Seclidemstat (SP-2577) for Myelodysplastic Syndrome (MDS) and Chronic Myelomonocytic Leukemia (CMML): Seclidemstat is also being evaluated in an investigator-initiated Phase 1/2 clinical trial at MD Anderson Cancer Center for the treatment of MDS and CMML, where patient enrollment has resumed after a partial clinical hold was lifted. Promising interim results have been reported for this combination therapy, indicating a potential for seclidemstat in these hematologic cancers.
  3. Development and Commercialization of Decoy Therapeutics' Peptide Conjugate Pipeline: With the merger, the combined entity will focus on Decoy Therapeutics' pipeline of peptide conjugate therapeutics. This pipeline targets unmet needs in respiratory infectious diseases and gastroenterology (GI) oncology, representing new and potentially significant market opportunities for the company.
  4. Integration and Clinical Advancement of SP-3164 as a PROTAC Drug Candidate: Salarius' small molecule protein degrader, SP-3164, which was expected to begin clinical trials in 2023 for hematological and solid tumors, will be integrated into Decoy's pipeline. This integration as a peptide-based proteolysis targeting chimera (PROTAC) drug candidate could leverage Decoy's platform to enhance its development and potential market entry.
  5. Potential Strategic Alternatives for Seclidemstat: The company is actively evaluating strategic alternatives for seclidemstat while continuing its development for hematologic cancers. This could involve partnerships, licensing agreements, or out-licensing deals, which could provide non-dilutive funding or royalty streams, contributing to future revenue.

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Share Issuance

  • Salarius Pharmaceuticals effected a 1-for-15 reverse stock split on August 15, 2025, to regain compliance with Nasdaq's minimum bid price requirement.
  • In September 2025, the company sold 434,882 shares of common stock for aggregate gross proceeds of $2.4 million under an at-the-market (ATM) agreement and 367,887 shares for $3.8 million under a private purchase agreement with C/M Capital Master Fund, LP.
  • In November 2025, Salarius Pharmaceuticals priced an underwritten public offering to raise approximately $7.0 million of gross proceeds through the sale of common shares and pre-funded warrants, each accompanied by Series A and Series B warrants.

Inbound Investments

  • In January 2025, Salarius Pharmaceuticals entered into a definitive merger agreement for a business combination with Decoy Therapeutics, Inc., a privately held preclinical biopharmaceutical company.
  • Under the terms of the merger, legacy Salarius stockholders are expected to retain approximately 7.6% of the combined company.
  • Decoy Therapeutics has secured financing from institutional investors and non-dilutive capital from entities such as the Massachusetts Life Sciences Seed Fund, the Google AI startup program, the NVIDIA Inception program, and a QuickFire Challenge award from BARDA.

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Peer Comparisons for Salarius Pharmaceuticals

Peers to compare with:

Financials

SLRXARVNKYMRNRIXCCCCGLUEMedian
NameSalarius.Arvinas Kymera T.Nurix Th.C4 Thera.Monte Ro. 
Mkt Price0.8412.4176.6918.492.2223.2815.45
Mkt Cap0.00.96.71.60.21.91.2
Rev LTM031244843018264
Op Inc LTM-5-102-328-267-1199-111
FCF LTM-4-330-230-241-95145-163
FCF 3Y Avg-9-310-184-168-94-13-131
CFO LTM-4-328-228-230-94149-161
CFO 3Y Avg-9-307-168-158-93-2-125

Growth & Margins

SLRXARVNKYMRNRIXCCCCGLUEMedian
NameSalarius.Arvinas Kymera T.Nurix Th.C4 Thera.Monte Ro. 
Rev Chg LTM-93.9%-50.1%48.3%-10.6%1,112.3%48.3%
Rev Chg 3Y Avg-40.2%12.9%35.1%-1.0%-24.0%
Rev Chg Q--59.1%-26.1%-37.3%-26.9%38.5%-26.9%
QoQ Delta Rev Chg LTM--16.2%-2.2%-5.3%-12.1%2.0%-5.3%
Op Mgn LTM--32.7%-750.9%-319.3%-395.4%4.7%-319.3%
Op Mgn 3Y Avg--150.1%-456.2%-297.8%-476.7%--377.0%
QoQ Delta Op Mgn LTM--0.9%-53.4%-58.6%-34.4%-3.7%-34.4%
CFO/Rev LTM--104.9%-521.2%-275.3%-313.8%82.2%-275.3%
CFO/Rev 3Y Avg--158.6%-328.2%-220.1%-358.5%--274.1%
FCF/Rev LTM--105.5%-526.4%-288.4%-315.2%79.9%-288.4%
FCF/Rev 3Y Avg--160.0%-355.5%-234.3%-364.1%--294.9%

Valuation

SLRXARVNKYMRNRIXCCCCGLUEMedian
NameSalarius.Arvinas Kymera T.Nurix Th.C4 Thera.Monte Ro. 
Mkt Cap0.00.96.71.60.21.91.2
P/S-2.9153.118.65.410.610.6
P/EBIT-0.1-8.9-22.7-5.8-1.5225.4-3.7
P/E-0.1-15.5-22.7-6.4-1.491.6-3.9
P/CFO-0.1-2.8-29.4-6.8-1.712.9-2.2
Total Yield-1,237.2%-6.4%-4.4%-15.7%-73.9%1.1%-11.1%
Dividend Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%
FCF Yield 3Y Avg-767.0%-24.0%-6.6%-16.8%-46.1%-14.4%-20.4%
D/E0.00.00.00.00.40.00.0
Net D/E-11.9-0.9-0.1-0.2-0.8-0.2-0.5

Returns

SLRXARVNKYMRNRIXCCCCGLUEMedian
NameSalarius.Arvinas Kymera T.Nurix Th.C4 Thera.Monte Ro. 
1M Rtn1.2%-6.8%-18.7%-13.9%-12.6%30.4%-9.7%
3M Rtn-79.6%27.3%36.2%85.3%-0.4%201.9%31.8%
6M Rtn-92.6%50.8%69.7%40.3%9.9%340.1%45.5%
12M Rtn-96.7%-36.1%87.4%-2.2%-42.5%256.8%-19.1%
3Y Rtn-99.7%-63.6%180.6%68.7%-67.0%192.5%2.6%
1M Excs Rtn1.1%-3.7%14.4%1.5%-17.6%33.0%1.3%
3M Excs Rtn-84.5%30.4%31.7%85.0%-4.8%212.4%31.0%
6M Excs Rtn-103.1%40.3%59.2%29.8%-0.6%329.6%35.0%
12M Excs Rtn-113.2%-55.9%67.9%-22.7%-59.8%208.2%-39.3%
3Y Excs Rtn-179.8%-144.0%127.0%-11.9%-142.6%125.7%-77.2%

Financials

Segment Financials

Revenue by Segment
$ Mil20242023202220212020
Developing treatments for cancers caused by dysregulated gene expression    3
Total    3


Assets by Segment
$ Mil20242023202220212020
Developing treatments for cancers caused by dysregulated gene expression7154125 
Total7154125 


Price Behavior

Price Behavior
Market Price$0.84 
Market Cap ($ Bil)0.0 
First Trading Date01/29/2015 
Distance from 52W High-98.5% 
   50 Days200 Days
DMA Price$1.36$7.19
DMA Trenddowndown
Distance from DMA-38.0%-88.3%
 3M1YR
Volatility169.6%203.5%
Downside Capture377.05206.72
Upside Capture-446.36-164.72
Correlation (SPY)13.9%-3.2%
SLRX Betas & Captures as of 12/31/2025

 1M2M3M6M1Y3Y
Beta3.392.061.631.29-0.34-0.07
Up Beta8.094.721.271.08-2.00-1.43
Down Beta6.133.653.022.800.651.29
Up Capture-219%-497%-262%-168%-46%-6%
Bmk +ve Days11233772143431
Stock +ve Days1016274795309
Down Capture509%486%353%319%148%106%
Bmk -ve Days11182755108320
Stock -ve Days11243679153419

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
 SLRX vs. Other Asset Classes (Last 1Y)
 SLRXSector ETFEquityGoldCommoditiesReal EstateBitcoin
Annualized Return-96.8%17.6%19.0%66.7%4.6%4.2%-4.4%
Annualized Volatility202.4%17.3%19.4%19.9%15.4%17.0%34.7%
Sharpe Ratio-0.900.770.772.450.090.080.00
Correlation With Other Assets -1.2%-3.3%-8.6%0.7%-0.1%-3.5%

ETFs used for asset classes: Sector ETF = XLV, Equity = SPY, Gold = GLD, Commodities = DBC, Real Estate = VNQ, Bitcoin = BTCUSD
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Based On 5-Year Data
 SLRX vs. Other Asset Classes (Last 5Y)
 SLRXSector ETFEquityGoldCommoditiesReal EstateBitcoin
Annualized Return-80.0%8.9%14.7%18.3%11.5%5.0%27.6%
Annualized Volatility141.2%14.5%17.1%15.7%18.8%18.9%48.5%
Sharpe Ratio-0.540.430.690.940.500.170.54
Correlation With Other Assets 2.5%4.7%-2.2%2.3%6.0%4.0%

ETFs used for asset classes: Sector ETF = XLV, Equity = SPY, Gold = GLD, Commodities = DBC, Real Estate = VNQ, Bitcoin = BTCUSD
Smart multi-asset allocation framework can stack odds in your favor. Learn How
Based On 10-Year Data
 SLRX vs. Other Asset Classes (Last 10Y)
 SLRXSector ETFEquityGoldCommoditiesReal EstateBitcoin
Annualized Return-75.2%10.0%14.6%14.9%6.8%5.0%71.1%
Annualized Volatility127.8%16.6%18.0%14.8%17.6%20.8%55.7%
Sharpe Ratio-0.490.490.700.830.310.210.91
Correlation With Other Assets 8.4%9.2%-2.4%5.0%10.0%3.9%

ETFs used for asset classes: Sector ETF = XLV, Equity = SPY, Gold = GLD, Commodities = DBC, Real Estate = VNQ, Bitcoin = BTCUSD
Smart multi-asset allocation framework can stack odds in your favor. Learn How

Short Interest

Short Interest: As Of Date12152025
Short Interest: Shares Quantity184,642
Short Interest: % Change Since 113020250.2%
Average Daily Volume360,632
Days-to-Cover Short Interest1
Basic Shares Quantity481,587
Short % of Basic Shares38.3%

Earnings Returns History

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 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
8/10/2023-5.9%27.6%22.0%
11/10/20223.8%17.4%0.0%
8/15/20222.2%-6.7%-8.2%
3/10/2022-26.6%-21.9%-25.7%
8/5/20216.6%9.9%40.8%
7/29/2020-11.1%0.0%-23.1%
SUMMARY STATS   
# Positive343
# Negative323
Median Positive3.8%13.6%22.0%
Median Negative-11.1%-14.3%-23.1%
Max Positive6.6%27.6%40.8%
Max Negative-26.6%-21.9%-25.7%

SEC Filings

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Report DateFiling DateFiling
09/30/202511/14/202510-Q (09/30/2025)
06/30/202508/12/202510-Q (06/30/2025)
03/31/202505/14/202510-Q (03/31/2025)
12/31/202403/21/202510-K (12/31/2024)
09/30/202411/14/202410-Q (09/30/2024)
06/30/202408/09/202410-Q (06/30/2024)
03/31/202405/13/202410-Q (03/31/2024)
12/31/202303/22/202410-K (12/31/2023)
09/30/202311/09/202310-Q (09/30/2023)
06/30/202308/10/202310-Q (06/30/2023)
03/31/202305/11/202310-Q (03/31/2023)
12/31/202203/27/202310-K (12/31/2022)
09/30/202211/10/202210-Q (09/30/2022)
06/30/202208/05/202210-Q (06/30/2022)
03/31/202205/12/202210-Q (03/31/2022)
12/31/202103/25/202210-K (12/31/2021)