Tearsheet

Bio-Rad Laboratories (BIO)


Market Price (2/14/2026): $256.63 | Market Cap: $6.9 Bil
Sector: Health Care | Industry: Life Sciences Tools & Services

Bio-Rad Laboratories (BIO)


Market Price (2/14/2026): $256.63
Market Cap: $6.9 Bil
Sector: Health Care
Industry: Life Sciences Tools & Services

Investment Highlights Why It Matters Detailed financial logic regarding cash flow yields vs trend-riding momentum.

0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 11%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 6.7%, FCF Yield is 5.4%
Weak multi-year price returns
2Y Excs Rtn is -57%, 3Y Excs Rtn is -111%
Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -2.6%
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 15%
  Key risks
BIO key risks include [1] its significant dependence on customer funding from government grants and research contracts and [2] the inherent exposures of its extensive international operations.
2 Low stock price volatility
Vol 12M is 44%
  
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Gene Editing & Therapy, Show more.
  
0 Attractive yield
Total YieldTotal Yield = Earnings Yield + Dividend Yield, Earnings Yield = Net Income / Market Cap Dividend Yield = Total Dividends / Market Cap is 11%, ERPEquity Risk Premium (ERP) = Total Yield - Risk Free Rate, Reflects the premium above risk free assets offered by the investment. is 6.7%, FCF Yield is 5.4%
1 Attractive cash flow generation
CFO/Rev LTMCash Flow from Operations / Revenue (Sales), Last Twelve Months (LTM) is 21%, FCF/Rev LTMFree Cash Flow / Revenue (Sales), Last Twelve Months (LTM) is 15%
2 Low stock price volatility
Vol 12M is 44%
3 Megatrend and thematic drivers
Megatrends include Biotechnology & Genomics, and Precision Medicine. Themes include Advanced Diagnostics, Gene Editing & Therapy, Show more.
4 Weak multi-year price returns
2Y Excs Rtn is -57%, 3Y Excs Rtn is -111%
5 Weak revenue growth
Rev Chg 3Y AvgRevenue Change % averaged over trailing 3 years is -2.6%
6 Key risks
BIO key risks include [1] its significant dependence on customer funding from government grants and research contracts and [2] the inherent exposures of its extensive international operations.

Valuation, Metrics & Events

Price Chart

Why The Stock Moved

Qualitative Assessment

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Bio-Rad Laboratories (BIO) stock has lost about 20% since 10/31/2025 because of the following key factors:

1. Fourth Quarter 2025 Earnings Miss

Bio-Rad Laboratories reported adjusted earnings per share (EPS) of $2.51 for the fourth quarter of 2025, which fell short of analysts' consensus estimates that ranged from $2.57 to $2.71 per share. This earnings miss indicated a clear near-term profit weakness and pressured the stock.

2. Gross and Operating Margin Compression

The company's Q4 2025 GAAP gross margin decreased to 49.8% from 51.2% in the prior year, and non-GAAP gross margin also slipped to 52.5% from 53.9%. Management attributed these declines to higher-than-anticipated supply chain costs, including elevated expedited freight, overtime, and inventory write-offs, reflecting execution-related pressures rather than structural issues. This also led to a decline in the non-GAAP operating margin to 12% in Q4 from 13.8% the prior year.

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Stock Movement Drivers

Fundamental Drivers

The -19.7% change in BIO stock from 10/31/2025 to 2/14/2026 was primarily driven by a -20.3% change in the company's P/S Multiple.
(LTM values as of)103120252142026Change
Stock Price ($)319.55256.63-19.7%
Change Contribution By: 
Total Revenues ($ Mil)2,5582,5831.0%
P/S Multiple3.42.7-20.3%
Shares Outstanding (Mil)2727-0.2%
Cumulative Contribution-19.7%

LTM = Last Twelve Months as of date shown

Market Drivers

10/31/2025 to 2/14/2026
ReturnCorrelation
BIO-19.7% 
Market (SPY)-0.0%26.8%
Sector (XLV)9.3%28.9%

Fundamental Drivers

The 6.1% change in BIO stock from 7/31/2025 to 2/14/2026 was primarily driven by a 135.4% change in the company's Net Income Margin (%).
(LTM values as of)73120252142026Change
Stock Price ($)241.95256.636.1%
Change Contribution By: 
Total Revenues ($ Mil)2,5542,5831.1%
Net Income Margin (%)12.5%29.4%135.4%
P/E Multiple20.69.1-55.9%
Shares Outstanding (Mil)27270.9%
Cumulative Contribution6.1%

LTM = Last Twelve Months as of date shown

Market Drivers

7/31/2025 to 2/14/2026
ReturnCorrelation
BIO6.0% 
Market (SPY)8.2%13.4%
Sector (XLV)21.4%37.4%

Fundamental Drivers

The -28.9% change in BIO stock from 1/31/2025 to 2/14/2026 was primarily driven by a -31.4% change in the company's P/S Multiple.
(LTM values as of)13120252142026Change
Stock Price ($)360.88256.63-28.9%
Change Contribution By: 
Total Revenues ($ Mil)2,5802,5830.1%
P/S Multiple3.92.7-31.4%
Shares Outstanding (Mil)28273.6%
Cumulative Contribution-28.9%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2025 to 2/14/2026
ReturnCorrelation
BIO-28.9% 
Market (SPY)14.3%44.7%
Sector (XLV)8.8%52.1%

Fundamental Drivers

The -45.1% change in BIO stock from 1/31/2023 to 2/14/2026 was primarily driven by a -45.9% change in the company's P/S Multiple.
(LTM values as of)13120232142026Change
Stock Price ($)467.46256.63-45.1%
Change Contribution By: 
Total Revenues ($ Mil)2,8052,583-7.9%
P/S Multiple5.02.7-45.9%
Shares Outstanding (Mil)302710.2%
Cumulative Contribution-45.1%

LTM = Last Twelve Months as of date shown

Market Drivers

1/31/2023 to 2/14/2026
ReturnCorrelation
BIO-45.1% 
Market (SPY)74.0%36.7%
Sector (XLV)23.7%46.8%

Return vs. Risk

Price Returns Compared

 202120222023202420252026Total [1]
Returns
BIO Return30%-44%-23%2%-8%-3%-50%
Peers Return27%-20%-11%-0%3%-5%-12%
S&P 500 Return27%-19%24%23%16%-0%82%

Monthly Win Rates [3]
BIO Win Rate58%42%58%42%58%0% 
Peers Win Rate72%40%43%50%52%20% 
S&P 500 Win Rate75%42%67%75%67%50% 

Max Drawdowns [4]
BIO Max Drawdown-6%-53%-36%-18%-34%-3% 
Peers Max Drawdown-6%-33%-32%-10%-27%-8% 
S&P 500 Max Drawdown-1%-25%-1%-2%-15%-1% 


[1] Cumulative total returns since the beginning of 2021
[2] Peers: TMO, DHR, A, ILMN, QGEN. See BIO Returns vs. Peers.
[3] Win Rate = % of calendar months in which monthly returns were positive
[4] Max drawdown represents maximum peak-to-trough decline within a year
[5] 2026 data is for the year up to 2/13/2026 (YTD)

How Low Can It Go

Unique KeyEventBIOS&P 500
2022 Inflation Shock2022 Inflation Shock  
2022 Inflation Shock% Loss% Loss-67.4%-25.4%
2022 Inflation Shock% Gain to Breakeven% Gain to Breakeven206.6%34.1%
2022 Inflation ShockTime to BreakevenTime to BreakevenNot Fully Recovered days464 days
2020 Covid Pandemic2020 Covid Pandemic  
2020 Covid Pandemic% Loss% Loss-21.8%-33.9%
2020 Covid Pandemic% Gain to Breakeven% Gain to Breakeven27.8%51.3%
2020 Covid PandemicTime to BreakevenTime to Breakeven35 days148 days
2018 Correction2018 Correction  
2018 Correction% Loss% Loss-32.5%-19.8%
2018 Correction% Gain to Breakeven% Gain to Breakeven48.2%24.7%
2018 CorrectionTime to BreakevenTime to Breakeven221 days120 days
2008 Global Financial Crisis2008 Global Financial Crisis  
2008 Global Financial Crisis% Loss% Loss-50.9%-56.8%
2008 Global Financial Crisis% Gain to Breakeven% Gain to Breakeven103.6%131.3%
2008 Global Financial CrisisTime to BreakevenTime to Breakeven401 days1,480 days

Compare to TMO, DHR, A, ILMN, QGEN

In The Past

Bio-Rad Laboratories's stock fell -67.4% during the 2022 Inflation Shock from a high on 9/2/2021. A -67.4% loss requires a 206.6% gain to breakeven.

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About Bio-Rad Laboratories (BIO)

Bio-Rad Laboratories, Inc. manufactures, and distributes life science research and clinical diagnostic products in the United States, Europe, Asia, Canada, and Latin America. The company operates through Life Science and Clinical Diagnostics segments. The Life Science segment develops, manufactures, and markets a range of reagents, apparatus, and laboratory instruments that are used in research techniques, biopharmaceutical production processes, and food testing regimes. It focuses on selected segments of the life sciences market in proteomics, genomics, biopharmaceutical production, cellular biology, and food safety. This segment serves universities and medical schools, industrial research organizations, government agencies, pharmaceutical manufacturers, biotechnology researchers, food producers, and food testing laboratories. The Clinical Diagnostics segment designs, manufactures, sells, and supports test systems, informatics systems, test kits, and specialized quality controls for clinical laboratories in the diagnostics market. This segment offers reagents, instruments, and software, which address specific niches within the in vitro diagnostics test market. It sells its products to reference laboratories, hospital laboratories, state newborn screening facilities, physicians' office laboratories, and transfusion laboratories. In addition, the company offers products and systems to separate complex chemical and biological materials, as well as to identify, analyze, and purify components. The company offers its products through its direct sales force, as well as through distributors, agents, brokers, and resellers. Bio-Rad Laboratories, Inc. was founded in 1952 and is headquartered in Hercules, California.

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Here are 1-3 brief analogies to describe Bio-Rad Laboratories:

  • A more focused Thermo Fisher Scientific.
  • The Intel inside every biotech and clinical diagnostics lab.
  • The Cisco for scientific and medical research labs.

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  • Life Science Research Instruments and Reagents: Provides a comprehensive range of systems, consumables, and reagents for cell biology, genomics, proteomics, and drug discovery research, including PCR, electrophoresis, western blotting, and chromatography solutions.
  • Clinical Diagnostics Systems and Reagents: Offers instruments, software, and reagents for disease screening, monitoring, and diagnosis in areas such as diabetes, autoimmune diseases, infectious diseases, and blood typing.

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Company: Bio-Rad Laboratories (BIO)

Bio-Rad Laboratories sells primarily to other companies and institutions, rather than directly to individuals. Due to the highly diversified nature of its customer base across the life science research and clinical diagnostics markets, Bio-Rad does not publicly disclose specific "major customer companies" that account for a significant portion of its revenue. Its sales are typically fragmented across thousands of laboratories and institutions globally.

Instead, Bio-Rad's customer base consists of a broad array of organizations within the following categories:

  • Pharmaceutical Companies: These companies utilize Bio-Rad's tools and reagents for drug discovery, development, and quality control.
  • Biotechnology Companies: Similar to pharmaceutical companies, biotech firms use Bio-Rad products for research, development, and manufacturing processes.
  • Hospitals and Clinical Diagnostic Laboratories: These entities use Bio-Rad's diagnostic products for disease detection, monitoring, and patient management.
  • University and Research Institutions: Academic and government-funded laboratories are significant customers, using Bio-Rad's life science products for fundamental and applied research.
  • Public Health Laboratories: These labs use diagnostic solutions for public health surveillance and disease control.
  • Food Safety Companies: Organizations involved in food production and safety testing use Bio-Rad products for detecting contaminants and ensuring quality.
  • Environmental Quality Control Companies: These firms utilize Bio-Rad's solutions for environmental monitoring and testing.

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Norman Schwartz, Chairman of the Board, Chief Executive Officer

Norman Schwartz has served as Bio-Rad Laboratories' President and Chief Executive Officer since 2003 and as Chairman of the Board since 2012. He is the son of David and Alice Schwartz, who co-founded Bio-Rad in 1952. He was Vice President from 1989 to 2002, Group Manager, Life Science, from 1997 to 2002, and Group Manager, Clinical Diagnostics, from 1993 to 1997.

Roop K. Lakkaraju, Executive Vice President, Chief Financial Officer

Roop K. Lakkaraju was appointed Executive Vice President and Chief Financial Officer of Bio-Rad Laboratories, effective April 15, 2024. Prior to joining Bio-Rad, he served as Executive Vice President and CFO at Benchmark Electronics since 2018. He has also held CFO and senior operational roles at other multinational companies including Support.com and Solectron. Mr. Lakkaraju began his career as an auditor with Grant Thornton and PricewaterhouseCoopers.

Jonathan DiVincenzo, President, Chief Operating Officer

Jonathan DiVincenzo serves as the President and Chief Operating Officer of Bio-Rad Laboratories.

Rajat Mehta, Executive Vice President, Global Commercial Operations

Rajat Mehta holds the position of Executive Vice President, Global Commercial Operations at Bio-Rad Laboratories.

Colleen Corey, Executive Vice President, Global Human Resources

Colleen Corey is the Executive Vice President, Global Human Resources at Bio-Rad Laboratories.

AI Analysis | Feedback

The key risks to Bio-Rad Laboratories' business include its significant dependence on customer funding, the inherent challenges and exposures of its extensive international operations, and intense competition coupled with the ongoing necessity for new product innovation.

The most significant risk stems from Bio-Rad Laboratories' substantial reliance on government grants and research contracts for funding among many of its customers, particularly within its Life Science segment. Reductions in government funding or capital spending by customers directly impact the company's sales. This dependence was recently evidenced by a currency-neutral sales decrease in the Life Science segment due to a constrained academic research and biotech funding environment.

A second major risk involves the complexities and exposures associated with Bio-Rad's extensive international operations. A substantial portion of the company's sales are generated globally, making it vulnerable to various international risks such as fluctuations in foreign currency exchange rates, changes in governmental regulations, import restrictions, and broader global economic and geopolitical conditions.

Finally, the highly competitive markets in which Bio-Rad Laboratories operates, alongside the continuous need for developing and marketing new or improved products, represent a crucial ongoing risk. The company's ability to compete effectively and innovate is vital for sustained success, with reports also highlighting potential gross margin compression if sales volumes and pricing do not stabilize.

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  • Spatial Biology and Advanced Single-Cell Analysis Platforms: Companies like 10x Genomics, NanoString Technologies, and Resolve Biosciences are rapidly advancing and commercializing platforms that allow researchers to analyze gene expression and protein levels with spatial resolution within tissues or at unprecedented single-cell depth. These integrated systems provide richer and more comprehensive biological insights compared to traditional bulk analysis methods (such as qPCR and Western blotting) and basic cell analysis tools that constitute a significant portion of Bio-Rad's life science research segment. As these sophisticated platforms gain wider adoption and become more integrated into standard research workflows, they could shift research funding and experimental design preferences away from Bio-Rad's core offerings, potentially diminishing demand for their instruments and reagents in these areas.
  • CRISPR-based Molecular Diagnostics: Emerging companies, including Sherlock Biosciences and Mammoth Biosciences, are developing diagnostic tests that leverage CRISPR technology for highly sensitive, specific, and rapid detection of pathogens, genetic mutations, and various biomarkers. These innovative platforms offer the potential for simplified workflows, lower costs, and faster turnaround times compared to traditional molecular diagnostic methods (e.g., PCR-based tests) and some immunoassay formats that are central to Bio-Rad's clinical diagnostics portfolio. If these CRISPR-based solutions achieve widespread adoption in clinical settings, they could disrupt Bio-Rad's market share in molecular diagnostics and infectious disease testing by offering more efficient and potentially decentralized alternatives.

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Bio-Rad Laboratories operates in two primary segments: Life Science and Clinical Diagnostics.

Life Science Segment

Bio-Rad's Life Science segment provides instruments, software, consumables, and reagents for areas such as cell biology, gene expression, protein purification, protein quantitation, drug discovery, food safety, and science education. These products are based on technologies for separating, purifying, identifying, analyzing, and amplifying biological materials. Bio-Rad estimates the worldwide sales for products in the markets they serve within the Life Science segment to be approximately $19 billion.

  • Electrophoresis Products: The global market for electrophoresis products (equipment and supplies) was valued at approximately $2.0 billion in 2024 and is projected to reach $3.0 billion by 2033. Other estimates place the global electrophoresis market at $3.29 billion in 2024, projected to reach $4.49 billion by 2030.
  • Polymerase Chain Reaction (PCR) Technologies: The global PCR technologies market size was valued at approximately $15.69 billion in 2023 and is expected to rise to $31.37 billion by 2032. Another source estimated the global polymerase chain reaction market size at $18.04 billion in 2025, forecasted to reach approximately $31.65 billion by 2034.
  • Chromatography Products: The global chromatography market, including instruments and consumables, was valued at $11.53 billion in 2024 and is projected to reach $22.35 billion by 2035. Specifically, the global chromatography instruments market size was estimated at $9.82 billion in 2023 and is projected to reach $13.80 billion by 2030. The global chromatography accessories & consumables market was valued at $6.10 billion in 2025 and is projected to reach $8.74 billion by 2030. The global chromatography columns market size was valued at $13.16 billion in 2024 and is projected to reach $21.46 billion by 2032.
  • Immunoassays (Life Science applications): While Bio-Rad offers immunoassays across both segments, the global immunoassay market was valued at $35.0 billion in 2023 and is projected to reach $61.6 billion by 2033.

Clinical Diagnostics Segment

Bio-Rad's Clinical Diagnostics segment designs, manufactures, markets, and supports test systems, informatics systems, test kits, and specialized quality controls for clinical laboratories in the global diagnostics market. This includes products for blood transfusion, diabetes monitoring, autoimmune, and infectious disease testing. Bio-Rad estimates the worldwide sales for products in the markets they serve within the Clinical Diagnostics segment to be approximately $16 billion.

  • Quality Controls: The global In Vitro Diagnostics (IVD) quality control market was valued at $1.58 billion in 2024 and is projected to reach $2.15 billion by 2030. Another report indicates the global IVD quality control market size was $1.3 billion in 2023 and is set to register growth to $1.9 billion by 2032.
  • Immunohematology / Blood Typing Products: Specific global market size for immunohematology or blood typing products was not explicitly found. However, it falls under the broader Clinical Diagnostics market.
  • Infectious Disease Testing: This is a significant application area for immunoassays and PCR technologies. The infectious disease application in the immunoassay industry alone held a 66.10% share of the immunoassay market in 2024.
  • Diabetes Monitoring/Testing: The global diabetes care devices market size was valued at $34.28 billion in 2024 and is expected to reach $66.82 billion by 2032. The global blood glucose monitoring system market size was valued at $17.20 billion in 2024 and is projected to grow to $27.73 billion by 2032.
  • Immunoassays (Clinical Diagnostics applications): The global immunoassay market size was valued at $35.0 billion in 2023 and is projected to reach $61.6 billion by 2033.

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Bio-Rad Laboratories (BIO) is expected to drive future revenue growth over the next 2-3 years through a combination of strategic acquisitions, the expansion and innovation of its Droplet Digital PCR (ddPCR) platforms, continued growth in its process chromatography and food safety businesses, and geographical market expansion.

1. Expansion and Innovation in Droplet Digital PCR (ddPCR)

Bio-Rad's Droplet Digital PCR (ddPCR) technology is a significant growth driver. The company has recently expanded its ddPCR offering through the acquisition of Stilla Technologies and the launch of new platforms like the QX Continuumâ„¢ ddPCR system and the QX700â„¢ series. These new instruments, along with an expanded portfolio of assays, reagents, and software, are designed to extend Bio-Rad's presence in genomics research and applied science markets, including oncology, infectious disease, genetic research, environmental testing, cell and gene therapy, and biopharma quality control workflows. Continued investment in refining operations, including lean initiatives and proactive cost management, also supports the growth potential of these advanced ddPCR products.

2. Growth in Process Chromatography Business

The process chromatography business has shown strong growth, with increased sales contributing to Bio-Rad's performance in recent quarters. This segment is expected to normalize to high single-digit growth in 2026, indicating continued positive contributions to revenue. The company is actively launching new products within this area, such as Nuvia wPrime 2A Media and Foresight Pro Prepacked Chromatography Columns, aimed at biomolecule purification and biotherapeutic production.

3. Strategic Acquisitions and Partnerships

Mergers and acquisitions play a vital role in Bio-Rad's expansion strategy, allowing the company to acquire complementary businesses or technologies to accelerate growth, gain specialized expertise, and consolidate market share. The recent acquisition of Stilla Technologies, which expanded Bio-Rad's ddPCR offering, exemplifies this strategy. Additionally, strategic partnerships, such as the extended agreement with Gencurix for ddPCR IVD oncology kits in Europe, are expected to expand market availability and contribute to revenue.

4. Geographical Market Expansion

Bio-Rad is actively pursuing geographical expansion, particularly in rapidly developing economies such as Asia-Pacific and Latin America, to capitalize on the increasing demand for life science research tools and clinical diagnostic products. This strategy includes establishing stronger distribution networks and direct sales operations to reach a broader customer base.

5. New Product Launches and Diversification in Clinical Diagnostics and Food Safety

Beyond ddPCR, Bio-Rad continues to diversify its revenue streams through new product launches across its Life Science and Clinical Diagnostics segments. In 2024, the company introduced numerous products, including oncology assay updates, new gene therapy kits, expanded tools for flow cytometry and cell research, and advancements in single-cell and digital PCR technology. The company is also strengthening its position in food safety with products like the dd-Check STEC Solution and EZ-Check Salmonella spp. Kit. While the Clinical Diagnostics segment has experienced some flatness due to factors like lower reimbursement rates in China, it is projected to return to growth in the fourth quarter of 2025, driven by the annualization of the China reimbursement headwind and expected revenues from its quality controls portfolio.

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Share Repurchases

  • Bio-Rad's board of directors approved a new share repurchase program in July 2023, authorizing the company to repurchase up to $500 million of its outstanding common stock. This followed the completion of a prior share repurchase program.
  • In July 2024, the available amount under the 2023 Share Repurchase Program was increased by an additional $500 million, making approximately $578 million available for repurchases as of July 31, 2024.
  • By the third quarter of 2025, Bio-Rad completed a significant share repurchase totaling over $715 million under its ongoing buyback program.

Share Issuance

  • Bio-Rad Laboratories' shares outstanding have shown a decline over the last few years, with 2024 shares outstanding at 0.028 billion, a 3.41% decrease from 2023. This trend continued into Q3 2025, with shares outstanding at 0.027 billion, representing a 3.79% year-over-year decline.

Outbound Investments

  • In August 2022, Bio-Rad acquired Curiosity Diagnostics, a developer of technology solutions for rapid, automated detection of infections using PCR assays.
  • In February 2025, Bio-Rad announced its intent to acquire Stilla Technologies, a developer of digital PCR solutions, to enhance its digital PCR product portfolio. This acquisition was expected to close by the end of the third quarter of 2025.
  • During 2024, Bio-Rad made strategic investments to expand its Droplet Digital PCR platform, including investments in Geneoscopy for colorectal cancer screening and Oncocyte for transplant monitoring assays. The company also acquired Saber Bio as part of its cell biology product development strategy.

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Unique Key

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Peer Comparisons

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Financials

BIOTMODHRAILMNQGENMedian
NameBio-Rad .Thermo F.Danaher Agilent .Illumina Qiagen  
Mkt Price256.63505.99212.25125.80116.1350.40169.03
Mkt Cap6.9191.3150.835.317.710.926.5
Rev LTM2,58343,73524,2686,9484,3432,0715,646
Op Inc LTM2198,0514,6131,4798165401,148
FCF LTM3756,1115,0171,1529314721,042
FCF 3Y Avg2866,8115,6121,333641402987
CFO LTM5327,6516,3181,5591,0796581,319
CFO 3Y Avg4548,3076,8971,6947985751,246

Growth & Margins

BIOTMODHRAILMNQGENMedian
NameBio-Rad .Thermo F.Danaher Agilent .Illumina Qiagen  
Rev Chg LTM0.7%3.2%2.2%6.7%-0.7%5.3%2.7%
Rev Chg 3Y Avg-2.6%-0.3%-1.9%0.6%-1.8%-2.1%-1.9%
Rev Chg Q3.9%4.9%4.4%9.4%5.0%6.1%5.0%
QoQ Delta Rev Chg LTM1.0%1.2%1.1%2.4%1.3%1.5%1.2%
Op Mgn LTM8.5%18.4%19.0%21.3%18.8%26.1%18.9%
Op Mgn 3Y Avg10.5%17.6%21.0%21.3%9.0%19.2%18.4%
QoQ Delta Op Mgn LTM-0.3%0.2%0.6%0.0%0.2%0.4%0.2%
CFO/Rev LTM20.6%17.5%26.0%22.4%24.8%31.8%23.6%
CFO/Rev 3Y Avg17.5%19.3%30.3%25.1%18.2%28.7%22.2%
FCF/Rev LTM14.5%14.0%20.7%16.6%21.4%22.8%18.6%
FCF/Rev 3Y Avg11.0%15.8%24.7%19.7%14.6%20.1%17.8%

Valuation

BIOTMODHRAILMNQGENMedian
NameBio-Rad .Thermo F.Danaher Agilent .Illumina Qiagen  
Mkt Cap6.9191.3150.835.317.710.926.5
P/S2.74.46.25.14.15.34.7
P/EBIT6.622.633.922.914.920.221.4
P/E9.129.143.127.120.827.027.0
P/CFO13.025.023.922.716.416.619.6
Total Yield11.0%3.4%2.3%4.5%4.8%3.7%4.1%
Dividend Yield0.0%0.0%0.0%0.8%0.0%0.0%0.0%
FCF Yield 3Y Avg3.3%3.3%3.4%3.4%3.1%4.0%3.3%
D/E0.20.20.10.10.10.20.2
Net D/E-0.00.20.10.00.10.00.0

Returns

BIOTMODHRAILMNQGENMedian
NameBio-Rad .Thermo F.Danaher Agilent .Illumina Qiagen  
1M Rtn-20.3%-19.0%-11.5%-13.1%-20.1%4.2%-16.1%
3M Rtn-18.0%-12.5%-3.9%-14.2%-3.8%13.5%-8.2%
6M Rtn-10.2%3.6%0.9%5.9%16.0%2.0%2.8%
12M Rtn-7.4%-4.5%3.5%-5.8%15.9%26.9%-0.5%
3Y Rtn-44.3%-9.9%-5.7%-15.2%-44.2%7.4%-12.6%
1M Excs Rtn-18.1%-17.3%-9.5%-12.5%-18.0%7.5%-14.9%
3M Excs Rtn-21.4%-13.7%-2.9%-16.6%-4.6%13.2%-9.1%
6M Excs Rtn-16.3%-1.2%-4.4%0.5%10.4%-2.9%-2.1%
12M Excs Rtn-30.8%-18.6%-7.3%-21.1%-0.8%13.0%-13.0%
3Y Excs Rtn-111.4%-78.0%-73.3%-82.7%-105.4%-60.6%-80.4%

Comparison Analyses

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Financials

Segment Financials

Revenue by Segment
$ Mil20252024202320222021
Clinical Diagnostics1,4891,4511,5161,3051,412
Life Science1,1781,3471,4011,232886
Other Operations446914
Total2,6712,8022,9222,5462,312


Operating Income by Segment
$ Mil20252024202320222021
Clinical Diagnostics764218182 148
Life Science664267320 72
Other Operations-1-2-1 -2
Research and development expense-247    
Selling, general and administrative expense-842    
Foreign currency exchange gains (losses), net    -2
Net corporate operating, interest and other expense, net not allocated to segments    -13
Other income (expense), net    26
Total338483500 230


Assets by Segment
$ Mil20252024202320222021
Other long-term assets8,11440614,7459,8474,863
Cash, short-term investments and other current assets2,2687191,4181,0981,234
Property, plant and equipment, net, and operating lease right-of-use assets7242,4397165367
Clinical Diagnostics4934493641,0661,076
Goodwill, net414680347292264
Life Science287270208607496
Other Operations011109
Total12,2994,96317,79912,9738,009


Price Behavior

Price Behavior
Market Price$256.56 
Market Cap ($ Bil)6.9 
First Trading Date02/27/1980 
Distance from 52W High-24.5% 
   50 Days200 Days
DMA Price$306.37$281.99
DMA Trendupdown
Distance from DMA-16.3%-9.0%
 3M1YR
Volatility35.8%43.6%
Downside Capture110.7595.43
Upside Capture-11.8175.49
Correlation (SPY)34.6%47.7%
BIO Betas & Captures as of 1/31/2026

 1M2M3M6M1Y3Y
Beta0.820.900.991.071.050.92
Up Beta2.122.171.481.611.361.05
Down Beta-0.360.010.250.650.740.69
Up Capture90%56%87%95%68%44%
Bmk +ve Days11223471142430
Stock +ve Days7142151110364
Down Capture207%178%144%119%109%104%
Bmk -ve Days9192754109321
Stock -ve Days13274074140387

[1] Upside and downside betas calculated using positive and negative benchmark daily returns respectively
Based On 1-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with BIO
BIO-16.7%44.6%-0.29-
Sector ETF (XLV)9.6%17.4%0.3752.2%
Equity (SPY)14.0%19.4%0.5545.4%
Gold (GLD)74.3%25.3%2.174.7%
Commodities (DBC)7.0%16.7%0.247.8%
Real Estate (VNQ)7.9%16.6%0.2841.1%
Bitcoin (BTCUSD)-29.8%44.9%-0.6518.3%

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Based On 5-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with BIO
BIO-16.2%36.3%-0.40-
Sector ETF (XLV)8.0%14.5%0.3752.8%
Equity (SPY)13.3%17.0%0.6244.9%
Gold (GLD)22.1%17.0%1.068.5%
Commodities (DBC)10.5%18.9%0.440.5%
Real Estate (VNQ)5.2%18.8%0.1841.6%
Bitcoin (BTCUSD)8.3%57.2%0.3718.5%

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Based On 10-Year Data
Annualized
Return
Annualized
Volatility
Sharpe
Ratio
Correlation
with BIO
BIO7.6%33.4%0.30-
Sector ETF (XLV)11.2%16.5%0.5653.3%
Equity (SPY)15.6%17.9%0.7547.9%
Gold (GLD)15.3%15.6%0.826.2%
Commodities (DBC)8.1%17.6%0.388.7%
Real Estate (VNQ)6.4%20.7%0.2735.7%
Bitcoin (BTCUSD)67.9%66.7%1.0712.4%

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Short Interest

Short Interest: As Of Date1302026
Short Interest: Shares Quantity0.8 Mil
Short Interest: % Change Since 11520263.4%
Average Daily Volume0.2 Mil
Days-to-Cover Short Interest3.3 days
Basic Shares Quantity27.0 Mil
Short % of Basic Shares3.0%

Earnings Returns History

Expand for More
 Forward Returns
Earnings Date1D Returns5D Returns21D Returns
2/12/2026   
10/29/2025-4.7%-3.0%0.6%
7/31/202517.6%9.6%23.1%
5/1/2025-1.7%0.2%-9.9%
2/13/2025-9.5%-8.6%-16.1%
10/30/20248.4%12.8%3.0%
8/1/2024-1.6%-3.8%-1.2%
5/7/2024-4.2%5.0%3.2%
...
SUMMARY STATS   
# Positive121010
# Negative111313
Median Positive3.4%5.4%3.1%
Median Negative-4.2%-3.8%-9.9%
Max Positive17.6%12.8%23.1%
Max Negative-16.7%-21.2%-20.3%

SEC Filings

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Report DateFiling DateFiling
12/31/202502/13/202610-K
09/30/202510/29/202510-Q
06/30/202507/31/202510-Q
03/31/202505/01/202510-Q
12/31/202402/14/202510-K
09/30/202410/31/202410-Q
06/30/202408/02/202410-Q
03/31/202405/08/202410-Q
12/31/202302/16/202410-K
09/30/202310/27/202310-Q
06/30/202308/04/202310-Q
03/31/202305/05/202310-Q
12/31/202202/17/202310-K
09/30/202210/28/202210-Q
06/30/202207/29/202210-Q
03/31/202204/29/202210-Q

Insider Activity

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#OwnerTitleHoldingActionFiling DatePriceSharesTransacted
Value
Value of
Held Shares
Form
1Barry, JamesEVP, President, LSGDirectSell11082025306.18700214,289156,055Form
2Crowley, MichaelEVP, GBL Commercial OperationsDirectSell3172025247.063,000741,1842,018,739Form